{"product_id":"medicinal-chemistry-paperback","title":"Medicinal chemistry - Paperback","description":"\u003cp\u003eby \u003cb\u003eSunitha N\u003c\/b\u003e (Author), \u003cb\u003eAppa Rao B\u003c\/b\u003e (Author)\u003c\/p\u003e\u003cp\u003eSYNTHESIS AND CHARACTERIZATION OF 3,5- DIMETHYL PYRAZOLEAIM: To synthesize 3,5- dimethyl pyrazole in the laboratory and characterize the crude and re-crystallized product.APPARATUS\/INSTRUMENT REQUIRED: Reflux condenser, round bottomed flask, beaker, glass rod, pipette, buchner funnel, filtering flask, water bath, watch glass, capillary tube, thiele's tube, thermometer, electronic balance, vacuum pump and filter paper.CHEMICALS REQUIRED: Acetyl acetone, hydrazine hydrate, ethyl alcohol and n-hexane\/petroleum ether.CHEMICAL REACTION: REACTION MECHANISM: PRINCIPLE: Substituted pyrazoles are prepared by condensation of 1,3-diketones with hydrazine. For example, acetyl acetone and hydrazine gives 3,5-dimethyl pyrazole. The enamine and imine formed undergo cyclization to yield the product.PROCEDURE: 1. Take 0.06 moles of hydrazine hydrate in a 250 ml flask.2. To this, add 25 mL of ethyl alcohol with constant stirring.3. Now place the flask in an ice-old water or ice-bath and wait for 10 minutes.\u003c\/p\u003e\u003cdiv\u003e\n\u003cstrong\u003eNumber of Pages:\u003c\/strong\u003e 80\u003c\/div\u003e\u003cdiv\u003e\n\u003cstrong\u003eDimensions:\u003c\/strong\u003e 0.19 x 9 x 6 IN\u003c\/div\u003e\u003cdiv\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e March 02, 2023\u003c\/div\u003e","brand":"Books by splitShops","offers":[{"title":"Default Title","offer_id":42733046333503,"sku":"9786206142058","price":81.22,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0105\/8226\/1823\/files\/55489d4b5422dfa67c045efc62e05d18.webp?v=1765134559","url":"https:\/\/dhlswag.com\/products\/medicinal-chemistry-paperback","provider":"BBB","version":"1.0","type":"link"}