by Ikram El Yazidi-Belkoura (Editor), Tony Lefebvre (Editor)
This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.
Number of Pages: 114
Dimensions: 0.44 x 9.61 x 6.69 IN
Publication Date: January 31, 2022