by David J. Kirkland (Editor)
The expertise of toxicologists and statisticians to provide a rigorous and practical account of the interpretation of mutagenicity test data has been drawn upon for this volume. Now, chemicals such as drugs, food additives and pesticides all need careful screening to eliminate potentially mutagenic compounds. Although guidelines exist on the performance of these tests, advice on data evolution is scarce. This niche is now filled by providing the statistical background necessary for toxicologists to understand, design and interpret mutagenicity tests. In addition to the nine chapters dealing with the different tests explained, there is an introductory chapter on some of the statistical principles included, a glossary of useful terms and an appendix providing vital information on the availability of computer software.